Hypertension in pregnancy - Pathology

Pathology:
Placenta:
Shows increased incidence of infarcts, hematomas, cogested chorionic villi, proliferative endarteritis and degeneration.

 Kidney:
Endothelial cell hyperplasia, exudation of WBC Reduced glomerular filtrastion.

Liver:
Periportal haemorrhages, ischaemic lesions, fibrin deposition. Evidence of DIC can also be seen.

Brain:
Multiple petechial to large haemorrhages, in cortex, pons, midbrain.

Heart:
Subendocardial petechial haemorrhages in myocardium. Dilated left ventricle if acute LVF has occurred.

Lungs:
Pulmonary edema.

Adrenal glands:
Haemorrhoges and necrosis in profound circulatory collapse.


-Hypertension in pregnancy-classification
-Hypertension in pregnancy-gestational hypertension
-Preeclampsia
-Eclampsia, preeclamsia superimposed on chronic hypertension
-Chronic hypertension
-Hypertension in pregnancy-etiology and pathogenesis
-Pathology
-Mild hypertension in pregnancy-prevention and management
-Severe hypertension in pregnancy-management
-Severe preeclampsia in pregnancy-management
-Complications of hypertension
-Antihypertensive therapy- centrally acting drugs
-Antihypertensive therapy-beta blockers, calcium channel blockers
-Antihypertensive therapy-alpha blockers, vasodilator, diuretics, ACE inhibitors
-Acute severe hypertension - treatment
-Eclampsia - signs and symptoms
-Eclampsia - management