Differential diagnosis of leukoplakia :
Keratosis:
-White skin cells due to hypopigmented keratosis with out
heteromorphism.
-Appear as ill-defined white spots with no or mild
infiltration.
-If the keratosis prolongs for long term it can turn into
leukoplakia etc lesions.
Oral lichen planus in
combination with genital lichen planus
-Can appear on genital skin or at mucocutaneous junction.
-Usually appears as polygonal flat purple or dark red
papules with glossy surface.
-HPE: colloid bodies, basal liquefaction, degeneration,
dermal infiltration of lymphocytes etc.
Atrophic lichen
sclerosis:
-Often occurs on labia.
-It is atrophic vulvar dystrophy.
-Appear as blue and white papules, integrated pale hypo
pigmented spots can be seen.
-Can involve anus and vagina to form a dumble – shaped
lesions.
-Itching will be minimal usually.
to be continued..
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