Vulval leukoplakia – part 5

Differential diagnosis of leukoplakia cont..:

Vulval vitiligo:

-Depigmented spots with clear boundaries can be seen.

-No keratosis or infiltration or itching.

-Same type of lesions can be on other parts of the body.

-HPE: complete lack of dopamine stained melanocytes in the basal layer.

-Easy to differentiate with leukoplakia.

 

Vulval neurodermatitis:

-Usually distributed on both sides of the outer labia.

-Conscious itching sensation will be present.

-Skin lesions can develop due to continuous scratching.

-HPE: changes of chronic dermatitis, thickening of skin layers can be seen. There will be no spindle shaped cells which will help in differentiating with leukoplakia.

 

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