Prostaglandins for uterine atony: PGF2 alfa- corboprost tromethamine can be used in case of uterine atony in injection form 250 micro g, intramuscularly.
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Can be repeated if needed at 15 to 90 min period, with maximum of 8 doses.
Side effects:
diarrhea, hypertention, vomiting, fever, flushing, tachycardia, pulmonary airway and vascular constriction etc.
Other alternatives are:
- Rectally administered PGE2 20 mg suppositories.
-Misoprostol, 1000 micro g per rectally, with mean response time 1 to 4 min.
Prostaglandins for late PPH :
Late PPH (post partum hemorrhage) is a serious uterine hemorrhage developing 1 to 2 weeks in puerperium.
The causes may be abnormal involution of placental site, placental polyp etc.
PGE1 (misoprostol) can be used in this condition to stop hemorrhage along with curettage.
Other uses are like maintaining patency of ductus arteriosus and for healing of peptic ulcers etc.
Prostaglandins-types
Prostaglandin-routes of administration
Prostaglandins- in inducing abortions
Prostaglandins-induction of labor
Cervidril, misoprostol
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Can be repeated if needed at 15 to 90 min period, with maximum of 8 doses.
Side effects:
diarrhea, hypertention, vomiting, fever, flushing, tachycardia, pulmonary airway and vascular constriction etc.
Other alternatives are:
- Rectally administered PGE2 20 mg suppositories.
-Misoprostol, 1000 micro g per rectally, with mean response time 1 to 4 min.
Prostaglandins for late PPH :
Late PPH (post partum hemorrhage) is a serious uterine hemorrhage developing 1 to 2 weeks in puerperium.
The causes may be abnormal involution of placental site, placental polyp etc.
PGE1 (misoprostol) can be used in this condition to stop hemorrhage along with curettage.
Other uses are like maintaining patency of ductus arteriosus and for healing of peptic ulcers etc.
Prostaglandins-types
Prostaglandin-routes of administration
Prostaglandins- in inducing abortions
Prostaglandins-induction of labor
Cervidril, misoprostol
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