Liver diseases in pregnancy - Anatomical and physiological changes

Among the medical complications of pregnancy, liver disease in pregnancy is comparatively a rare complication.
But when liver disease occurs in pregnancy may progress in a dramatic and tragic fashion and can affect both mother and infant. If left untreated, can progress to jaundice, liver failure, and death.

Liver diseases in pregnancy:
 Some of the normal physiologic changes of pregnancy can mimic abnormalities associated with liver disease.
Telangiectasia, particularly on the chest, back, face and palmer erythema occur in up to 60 percent of normal pregnant women but disappear after delivery.
Extreme vigilance is needed. Prompt management can save the life of the mother and the baby.

Anatomic Changes:
Detection of hepatomegaly is strong evidence for the presence of liver disease.

Physiological changes:
Hepatic blood flow is maintained at a constant rate in pregnancy despite marked changes in the cardiovascular system.
Blood flow increases to the kidneys and other organs, but hepatic blood flow is unaltered, which results in a decline of approximately 35% in the proportion of cardiac output delivered to the liver.


-Liver-diseases in pregnancy-anatomical and physiological changes
-Biochemical changes
-summary of physiological and biochemical changes
-Spectrum of liver diseases in pregnancy
-Pre existent liver diseases in pregnancy -1
-Preexisting liver diseases in pregnancy -2