Sunday, 1 December 2013

Liver diseases in pregnancy - Preexistent liver diseases part-1

Portal hypertension, cirrhosis: Pregnancy is uncommon in women with preexisting portal hypertension and cirrhosis.
A life-threatening complication of liver cirrhosis is variceal bleeding associated with portal hypertension.
Oesophageal varices

The presence of severe portal hypertension with esophageal varices is associated with an increased risk of hemorrhage during pregnancy.
Treating bleeding esophageal varices with nonselective beta-blockers, band ligation, and octreotide is safe and effective during pregnancy.
The use of sclerotherapy for bleeding varices during pregnancy may provide a safe alternative to portacaval anastomosis and has been reported to be effective.

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