Clinzen in pregnancy

Some people think that clinzen vaginal tablets can lead to miscarriage.

These are frequently prescribed tablets for vaginal infection especially candidiasis.

Clinzen vaginal tablets or cream contain Clindamycin phosphate which is a water soluble ester of the semi-synthetic antibiotic.

It is Category B drug in pregnancy.

There are no adequate and well controlled studies regarding its usage in first trimester of preganacy. It should be used only if clearly indicated.

In second trimester in women treated with clinzen for 7 days abnormal labor reported in 1.1% of women.

As such overall reproductive studies on humans revealed no harm to the fetus. But studies on only one mouse strain reported cleft palate with other strains being not effected.

So, this can be taken as strain specific.

In general hospital practice this is used frequently and not connected to miscarriage.