The possible causes of IVF failure and solutions

The possible causes of IVF(in vitro fertilization) failure or implantation failure are,

1.    In case of PCOD:

 Anovlation is the feature of PCOD. 

And ovulation induction drugs to be used generally.

As there is anovulation, doctors will super ovulate in these patients which will lead to poor quality ovum or

Most of the doctors will think of ovulation hyperstimulation syndrome and they induce less number of ovum. 

Solution:

This can be overcome by careful aspiration of ovum from follicles  and removing follicular cells around it.

2.  Transferring usual number of embryos as in normal patients will not be sufficient in IVF failure cases.

Solution:

So more number of embryos to be transferred in these patients as the chance of high-order multiple pregnancy is less in them.

3.Sometimes patients will have poor ovarian reserve,

Solution:

This can be overcome by aggressive super-ovulation or

by GIFT- gamete intrafallopian transfer.

4. In case of technical difficulties for embryo transfer like cervical stenosis,

Solution: ZIFT- zygote  intrafallopian transfer can be done.

5.Sometimes chromosomal abnormalities will be there in even good looking embryos which lead to failure of IVF.

Solution:

This can be overcome by taking embryo biopsy on 3^rd day by laser and transferring the embryo on 5^th day.